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   Pain and Neem
 

Inhibition of prostaglandin synthetase by limonoids (and/or polysaccharides) reduces perceived pain.

Both as topical applications and as oral medicines, Neem provides a low cost pain reliever and fever-reducing remedy.

Neem leaf and bark extracts have been shown to be a more potent inhibitor of prostaglandin synthetase than acetylsalicylic acid (aspirin) and pethidine hydrochloride. (Okpako, 1977); (Pillai, 1978b); (Tandan, et al, 1990).

In some cases neem was effective at reducing pain for a significantly longer period than standard agents. Neem also reduces the activity of the central nervous system, which also reduces perceived pain (Debelmas, 1976).

According to a study led by N. Khanna, neem produces an analgesic effect upon the central and peripheral neural pathways. He also feels that both opioid and non-opioid receptors can be affected by neem.(Khanna et al, 1995)

Nimbin: anti-inflammatory, anti-pyretic,
anti-histamine, anti-fungal
Nimbidin: anti-bacterial, anti-ulcer, analgesic,
anti-arrhythmic, anti-fungal
Ninbidol: anti-tubercular, anti-protozoan,
anti-pyretic
Gedunin: vasodilator, anti-malarial, anti-fungal
Sodium nimbinate: diuretic, spermicide,
anti-arthritic
Quercetin: anti-protozoal
Salannin: insect repellent
Azadirachtin: insect repellent, anti-feedant,
anti-hormonal

This is a PDF file to read this you will require. You can download ACROBAT READER free HERE
Indian Journal of Pharmacology
2000; 32: 372-374 - ANTINOCICEPTIVE ACTIVITY OF AZADIRACHTA INDICA (NEEM) IN RATS....READ  


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NeemWell Creams, Lotions Oil, Leaves and Shampoo
are safe for topical use on all age groups.
Neem leaf capsules should not be given to
anyone under the age of 14
Our products are to support healing,
not to replace a practitioner.

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